In recent years, the treatment of premature ejaculation patients in many hospitals almost uniformly uses dorsal penile nerve blocking, so how effective is this treatment method for premature ejaculation? Theoretically, blocking the dorsal penile nerve can reduce the sensitivity of the glans penis and should have a good therapeutic effect on patients with premature ejaculation, but it is not, because premature ejaculation is a complex cause for patients and cannot be expected to be completely solved by cutting the nerve, which may have some effect in the short term (usually 4-6 months), but its long-term effect still needs further observation and research. Moreover, there is no definite conclusion on whether cutting the dorsal penile nerve has a negative effect on sexual performance. Physiologically speaking, the nerve that controls erection is the vegetative nerve, while the dorsal penile nerve is the somatic nerve, which is mainly related to pain and sensation in the body. However, some people think that after blocking the dorsal penile nerve, the sensation of the glans penis is dulled and the central afferent function to local sexual stimulation is weakened, and sometimes there may be some effect on erection. However, whether there is an effect and how big this effect is needs further evaluation and research. Therefore, patients with premature ejaculation are advised to choose dorsal penile nerve block with caution. Patients who have already undergone dorsal penile nerve block do not need to worry, as most patients will experience varying degrees of local sensation recovery about six months after surgery.