Uneven nails with small pits may be related to anemia, psoriasis, onychomycosis and other factors, need to identify the cause of the disease and then targeted treatment, common treatment drugs are hydrocortisone cream, ketoconazole, itraconazole and so on. 1. Anemia: the patient’s nails may become thin and concave in the center, bulging around, forming spatulate nails. There are many factors leading to anemia, and it is necessary to clarify the cause of the disease and then target the treatment, such as the use of vitamin B12, folic acid, iron and other medications under the guidance of the doctor. 2. Psoriasis: rough nails, “thimble-like” depression, separation and other symptoms, patients need to adhere to standardized treatment under the guidance of a doctor, commonly used drugs such as hydrocortisone cream, mometasone, halometasone and other topical glucocorticoid drugs. 3. ringworm of the nail: commonly known as “gray nails”, is caused by dermatophytes invade the nail plate and nail lesions, can be manifested as nail discoloration, shedding, warping, surface unevenness and other symptoms, need to use ketoconazole, miconazole nitrate and other medications under the guidance of a doctor to apply externally, if necessary, with the oral itraconazole, terbinafine, and other antifungal drug therapy. Uneven nails with small pits may also be due to chronic eczema, lichen planus, diabetes and other diseases, it is recommended that patients seek medical attention in a timely manner, and actively cooperate with the relevant examination, in order to clarify the cause of the symptomatic treatment, and to avoid self-medication, so as not to delay the condition.