Patient: Description (onset, main symptoms, hospital visited, etc.): It has been nearly three months since the onset of the disease. I have consulted different hospitals and doctors, and first suspected nephrotic syndrome, then diagnosed acute glomerulonephritis, and also some hospitals suspected IgA nephropathy. I would like to get a definite cause and treatment plan. Shen Tong, Department of Pediatrics, Xiamen Maternal and Child Health Hospital: The main manifestations of nephrotic syndrome are: 1) massive proteinuria: >50mg/kg/day, 2) hypoalbuminemia, <25g/L, 3) hyperlipidemia, 4) swelling, of which massive proteinuria and hypoalbuminemia are necessary conditions, I wonder what is the weight of the child? How much is the blood albumin? Is it possible to reach the diagnosis of nephrotic syndrome? The child presents with hematuria and proteinuria with swelling and decreased blood complement. If the child is a girl, attention should be paid to differentiate her from systemic lupus erythematosus nephritis. It is recommended to follow up with further examination at the hospital and recheck blood complement and urine protein quantification to further clarify the diagnosis.