Chest pain during pregnancy is defined as chest pain that occurs during pregnancy. Most of the chest pains that occur during pregnancy have anterior cardiac pain or angina pectoris as the clinical manifestation. It is caused by gestational myocardial infarction. Myocardial infarction of pregnancy is a rare complication of pregnancy. It is rarely reported in China. This type of myocardial infarction is different from other types of myocardial infarction because it not only endangers the life of the pregnant woman, but also poses a threat to the fetus. How to effectively prevent chest pain during pregnancy? (1) Treatment 1. Thrombolytic therapy can be performed at an early stage if necessary for high-risk patients (1) Diuretics can be used in principle, but attention should be paid to the low potassium and sodium in the fetus, so it is appropriate to apply them in small doses for a short period of time. (2) Anticoagulants are generally not used. Heparin can lead to premature birth or intrauterine death in 1/3 of affected children, but it does not affect fetal development and is not secreted from breast milk. (3) The application of digitalis drugs. It can induce uterine contractions and has the potential to induce miscarriage in the early stages of pregnancy (1 to 3 months). Small doses of digoxin are safe. (4) Anti-arrhythmic drugs. Generally not used unless necessary, as all antiarrhythmic drugs are secreted through the placenta and breast milk. (5) Beta blockers are safe drugs for pregnancy and can be applied in small amounts depending on the condition. (6) Cesarean delivery should be performed in patients who have acute ischemia or unstable hemodynamics despite adequate medical therapy. (7) Nitrates and calcium antagonists should be used with caution to avoid hypotension and the possibility of fetal distress. (8) High doses of enteric aspirin may cause bleeding in the newborn and mother, but small doses of aspirin may be used when necessary. (9) Pregnancy should be terminated in patients with intractable ischemia and heart failure in early pregnancy. (10) Percutaneous coronary angioplasty or coronary artery bypass grafting can be performed if medications are ineffective. (11) Application of electric defibrillation: it is safer and can be applied in all stages of pregnancy. 2. Matters related to myocardial infarction in pregnancy (1) When myocardial infarction in pregnancy has no complications, full-term pregnancy is possible. (2) If termination of pregnancy is necessary, it should be performed 6 weeks after the onset of acute myocardial infarction to prevent the occurrence of cardiac arrest. (3) The choice of anesthesia for termination of pregnancy: (1) in the first to sixth month of pregnancy, the same choice as for non-pregnant; (2) in the seventh to ninth month of pregnancy, local anesthesia is mostly chosen, which has less impact on the heart. In addition, postpartum myocardial infarction, mostly occurs within 10 days after delivery, the site of infarction is mostly in the anterior wall, the etiology is unknown, the diagnosis and treatment are the same as acute myocardial infarction, and the application of drugs should take into account the characteristics of infant medication. (ii) Prognosis Ginz synthesized the literature from 1922 to 1970, 36 cases of myocardial infarction in pregnancy, including 3 cases under his own observation, for a total of 39 cases. The results of the analysis were that the incidence was 1 in 10,000 pregnancies and the mortality rate was slightly less than 30%; the highest mortality rate was in patients in the puerperium, and surprisingly the age of those who died was under 35 years. Salem et al. observed a relationship between the timing of myocardial infarction and pregnancy, and they concluded that postpartum myocardial infarction occurs mostly in primiparous women and prenatal myocardial infarction mainly in menstruating women, and that most postpartum myocardial infarction is perimural rather than subendocardial. grofishe and Gensini reviewed data on 54 myocardial infarction cases, 45 of which were perimural, and in Of the surviving cases, the morbidity and mortality rate was 43% in patients aged 30 years or younger, compared with 34% in those older than 30 years. The occurrence of myocardial infarction in the second trimester of pregnancy mainly affects maternal survival. Two-thirds of women with myocardial infarction in the third trimester (9 months) died, with a 45% mortality rate. In turn, maternal mortality was significantly higher in women with myocardial infarction in the 9th month of pregnancy and in those who delivered within 14 days of myocardial infarction. The results of previous studies suggest that approximately 60% of women who die of heart disease do so suddenly, and therefore sudden death in pregnant women should be considered a heart attack, especially in women with chest pain during pregnancy, where the possibility of angina pectoris or myocardial infarction should be highly guarded.