The principle of treatment for HPV infection is “treat the disease, not the virus”! There is no need to treat lesions that are not visually or pathologically confirmed. In other words, treatment is only needed if there are visible lesions (e.g., condyloma acuminatum) or pathologically confirmed lesions (e.g., CIN). Corresponding to the types of HPV infection mentioned above, it means that latent infection and subclinical infection do not require treatment. The above paragraph is the worldwide consensus! All treatments only target the lesions caused by HPV, not the HPV virus itself! Our clinical guidelines also do not say to treat HPV alone with antiviral therapy. Therefore, the most common question people ask: Do I need treatment if HPV infection is found on physical examination? The answer is as follows: If there is no problem with other tests such as TCT, it is just a simple HPV infection and does not require any treatment, just review it regularly!