Cardiac atherosclerosis can present with coronary heart disease and a risk of acute myocardial infarction. Atherosclerosis of the cerebral arteries carries a risk of stroke. With atherosclerotic stenosis of the renal arteries, you may have intractable hypertension and may develop renal insufficiency with prolonged stenosis. Progression of atheromatous plaque in the extremities can be associated with adverse limb movement and ulcers.