Facial muscle spasm, also known as facial muscle twitching (face twitching), mainly manifests as recurrent, episodic involuntary contractions of the muscles innervated by the facial nerve. It can develop in both men and women, mostly in adulthood, with a high incidence between the ages of 30 and 40. Facial myoclonus is characterized by paroxysmal contractures on one side of the face, often starting from the orbicularis oculi, and gradually developing in the lower half of the face, with mood swings, mouth slanting, fatigue of the eye fissure on the diseased side, and becoming smaller and more aggravated. The clinical manifestation of facial muscle spasm is intermittent, fixed side of the facial muscle twitching, orbicularis oculi is often the first site, as the disease progresses, the twitching range gradually expanded to involve the face, the corners of the mouth and other broad neck muscles and muscles. The twitching may last for several seconds or minutes. The attack can be aggravated by excessive fatigue, stress, and emotional stress. There is no pain during the attack, but if it is severe, there is deep discomfort due to twitching at the corners of the mouth, eyelid spasms, preventing speech, vision, and eating, sometimes accompanied by tinnitus, headache, nasal congestion, and sweating. The twitching will stop when the patient falls asleep. Neurological examination reveals no positive signs in most primary cases. However, asking them to show their teeth or forcefully close their eyes can often trigger facial muscle twitching. In secondary patients, the corresponding signs can be detected depending on the original cause. The interval between seizures varies from several days to several months. Patients look like normal people during the interval, but rarely do they heal spontaneously and remit completely.