Secondary hypertension China has a large hypertensive population, and there are currently about 200 million people with hypertension in China. The majority of hypertensive patients are currently receiving medication to lower their blood pressure. When people suffer from hypertension, that means a lifetime of medication treatment, antihypertensive drugs become a must for home travel. Traditionally, people may not realize that the cause of hypertension can be found and cured by surgical means. With the advancement of medical technology today, more and more causes of hypertension are being discovered. When the cause is identified and controlled or removed by surgical means, most of hypertension as a secondary symptom can be cured or significantly improved. 1, the classification of secondary hypertension: (1) endocrine diseases: such as adrenal gland disease. Commonly, primary aldosteronism, pheochromocytoma, Cushing’s syndrome, hyperthyroidism, Hashimoto’s thyroiditis, renin-secreting tumor pituitary tumor, etc.; (2) renal hypertension: including the substantive lesions of the kidney, such as various types of nephritis, chronic pyelonephritis, giant hydronephrosis, polycystic kidney, kidney stones, renal tuberculosis, renal tumors, etc.; (3) renal vascular diseases: such as renal artery atherosclerosis, (4) obstructive sleep apnea syndrome; (5) cardiovascular diseases, such as aortic valve insufficiency, aortic constriction, etc.; (6) systemic diseases, such as rheumatism, systemic lupus erythematosus, scleroderma, etc.; diabetes, gout and other metabolic diseases; (7) neurological diseases, such as increased cranial pressure, mesencephalic syndrome, spinal cord transverse injury, etc. syndrome, transverse spinal cord injury, etc. (2) Clinical manifestations of secondary hypertension: In clinical work, if you encounter hypertensive patients with the following characteristics, you should focus on the possibility of secondary hypertension. (1) middle-aged or young patients <40 years old with moderate or severe elevation of blood pressure; (2) poor efficacy of antihypertensive drugs, needing multiple antihypertensive drugs to control or easy fluctuation of blood pressure; (3) accompanied by the following symptoms or characteristics: such as muscle weakness, periodic limb paralysis, increased nocturia; paroxysmal hypertension with headache, palpitations, excessive sweating; full moon face, buffalo back, purple skin and polycythemia appearance; obvious fear of heat, excessive sweating, and (4) Acute and malignant hypertension, with rapid progression of the disease, severe target organ damage, cardiovascular and cerebrovascular events within a relatively short period of time, urine protein positive, fundus damage, etc. Patients with these characteristics should be screened for secondary causes of hypertension. Combining the patient's medical history, physical signs, clinical manifestations, and routine ancillary examinations such as routine blood, blood biochemistry, lipids, renal and adrenal ultrasound, preliminary clues for secondary hypertension are sought. For those who suspected the possibility of secondary hypertension, further correlation was continued to clarify the etiology.