The first thing to consider in this case is that the infusion is caused by one or more factors such as low temperature of the medication, impurities, high concentration of the medication during intravenous infusion, as well as the speed of the infusion and contamination of the infusion bottle. In this case, the infusion should be slowed down immediately, warmed up promptly, treated with anti-allergy medication if necessary and stopped immediately if the reaction is severe.