Patient: Female, 32 years old, first hyperthyroidism was onset in April 2001, in the middle of the treatment for 1 year in 2004 after the relapse, and then take medication for 3 years in December 2007 after stopping medication, stopping medication for 2 months after pregnancy and hyperthyroidism relapse, this relapse time is March 2008 (at that time pregnant, then do the operation of retaining the birth of a baby), during the period of time, has been in the medication (now taking propylthiomidine 1 tablet / day, just relapse 6 tablets /day). 1.If the joint pain is caused by the side effect of the medicine, which medicine should I change? 2. Will long-term use of the medication cause irreparable damage to the joints? I stopped taking propylthiomidine for 2 weeks and switched to Cytotec, and my knee is still not healed, so I’m not sure if it’s a side effect of the medication? 3.Which treatment is better for me in my current situation? 4.Iodine-131 treatment is feasible? All the indicators of my hyperthyroidism are normal, can I do 131 treatment in this case? 5.Which one is less harmful to my body, hypothyroidism or hyperthyroidism? 6. Is Iodine-131 treatment very painful? I don’t have any children yet, can I have a child after 6 months of Iodine-131 treatment? 8.If I find hypothyroidism or hyperthyroidism recurring after pregnancy, can I take medication? There are so many questions, please include more. Thank you very much! The free thyroxine result was 12.59; free triiodothyronine 4.38; thyrotropin 2.20. These values are within the normal range, and the doctor said that the control is good. HOSPITALIST: Your joint pain is a side effect of the anti-thyroid medication, which is more severe with Propecia and slightly less severe with Cytomel… Didn’t your internist tell you that? You have been on medication for 7 years with poor results and side effects, haven’t you thought of a different method of treatment? You should go for Iodine-131 treatment to cure hyperthyroidism and get pregnant as soon as possible. Iodine-131 treatment is just drinking a sip of water or swallowing a capsule, no pain. Don’t be afraid of hypothyroidism, hypothyroidism correctly supplement thyroxine as normal people, because thyroxine is T4, is a necessary component of the body, normal use will not have side effects. Iodine-131 treatment after six months can be pregnant, pregnant to check once a month FT3, FT3, TSH, according to the situation of the symptomatic treatment, hypothyroidism using thyroxine replacement will not affect the development of the fetus, mild hyperthyroidism can be controlled by medication, severe hyperthyroidism will have to take a great risk and the child does not dare to insure that there is no problem.