Acne vulgaris can be treated with medications such as retinoids, antibiotics and other creams. 1. Retinoids: e.g. retinoic acid ointment, adapalene gel, for common acne, especially blackheads and acne lesions. Adverse effects may cause skin irritation such as burning sensation, erythema and flaking. It is contraindicated in women during the first trimester of pregnancy, and in patients with acute or subacute dermatitis eczema-type skin diseases. 2. Antibiotics: such as fusidic acid cream and mupirocin ointment are effective against Propionibacterium acnes, so they can treat acne. Adverse reactions may cause contact dermatitis such as rashes and itching, and those who are allergic to the ingredients are prohibited from using them. 3. Other categories: benzoyl peroxide gel has the effect of killing Propionibacterium acnes, dissolving acne and astringent, azelaic acid has a therapeutic effect on inflammation and acne, and can also reduce post-inflammatory hyperpigmentation.2 Selenium disulfide lotion has the effect of inhibiting fungi, parasites, and bacteria, and can reduce the skin free fatty acid content. Adverse reactions are skin erythema, dryness and itching, burning and stinging. It is contraindicated for those who are allergic to the ingredients. It is recommended that acne acne patients first go to the hospital for examination, drugs need to be used under the guidance of a doctor, do not self-medication.