The drugs that tend to cause localized ischemic colitis are alosetron, 5-hydroxytryptamine receptor antagonists. Alosetron causes dysbiosis of the intestinal flora and proliferates non-pathogenic bacteria. Localized ischemic colitis can be divided into vaso-obstructive and non-vascular obstructive types, which are a series of inflammatory reactions and injuries inside the colon due to insufficient blood supply. When the symptoms of ischemic colitis are diarrhea, abdominal pain and bleeding in the colon, you can go to the hospital for a colonoscopy, and then use antibiotics and blood-stasis-boosting drugs to treat the symptoms. The severity of the symptoms of local ischemic colitis depends mainly on the severity of ischemia, appropriate exercise to promote blood circulation, and then to avoid overexertion, when suffering from unexplained symptoms of blood in the stool should immediately go to the hospital for treatment.