Using laser to remove colored moles is safer and more thorough than potions. The so-called medicine mole spotting is actually using strong corrosive liquid (mostly strong acid or alkali) to make the local skin tissue necrotic and fall off. Firstly, in terms of therapeutic effect, it often fails to remove the mole completely, has a high chance of recurrence, and may even stimulate the mole cells to trigger malignant changes. Secondly, such chemical substances may also lead to dermatitis, and the use of unclean tools may also lead to skin infections. Laser mole spotting, on the other hand, uses carbon dioxide laser to generate high energy to vaporize the tissue precisely and controllably to achieve the purpose of removing the mole. The process is simple and inexpensive, and if it is not a mole with a large area or a deep location, it will not leave a scar, and the recovery after the operation is also faster. Comprehensive comparison, it is recommended to go to a regular hospital under the guidance of a doctor to use laser mole spotting, and follow the doctor’s instructions for care.