Atrophic vaginitis is characterized by abnormal vaginal discharge, vaginal dryness, vaginal bleeding, local pain or itching, etc. It is generally caused by low estrogen level in the body. If there is no contraindication, it can be relieved by topical medication to supplement estrogen or regulate the vaginal flora. Atrophic vaginitis is a kind of vaginitis caused by the atrophy of vaginal glandular epithelial cells and dysfunction of vaginal flora due to the low level of estrogen, which may result in abnormal vaginal secretion, such as vaginal dryness, or increase in vaginal secretion, which is dilute and watery, yellowish in color, and in severe cases, accompanied by vaginal bleeding, odor, burning, itching and redness of vulva, etc., which may be accompanied by pain of sexual intercourse and frequent urination and pain in urination. Atrophic vaginitis is mostly treated by combining estrogen ointment, Prostaglandin cream and other local topical application, oral low-dose estrogen, or vaginal Lactobacillus capsules to regulate the vaginal flora, etc. to improve the symptoms and treat the disease. It should be noted that the combination of estrogen ointment, Prostacyclin cream is a topical estrogenic drug, the use of which may have local itching, burning sensation and other adverse reactions. The use of drugs need to follow the doctor’s instructions, to exclude drug contraindications. Estrogenic drugs should not be used more than once to avoid increasing the chance of estrogen-dependent diseases, such as endometriosis. Patients with atrophic vaginitis should use medication under the guidance of a doctor, and should not use medication blindly.