LAD mid-segment myocardial bridge mainly refers to the occurrence of coronary artery myocardial bridge in the middle of the descending branch, which belongs to a kind of congenital coronary artery development abnormality. When LAD myocardial bridge occurs, patients may experience angina-like symptoms, accompanied by cardiac arrhythmia, manifested as panic, shortness of breath, chest tightness, and a small number of patients may experience symptoms such as increased blood pressure, cold and clammy skin, etc., which may induce myocardial infarction or sudden death after further progression. When LAD middle myocardial bridge is detected, treatment needs to be carried out as early as possible, mainly including drug treatment, interventional therapy, and surgical treatment. Drugs should be symptomatic, when there is panic and rapid heartbeat, beta-blockers, such as metoprolol, bisoprolol antiarrhythmic can be taken. For more severe myocardial bridges, interventional therapy or coronary artery bypass grafting or myocardial bridge release therapy is needed. Diagnosis of mid-segment myocardial bridge requires timely consultation and selection of the best treatment under the guidance of a specialized physician, during which regular review is required to prevent myocardial infarction and sudden death.