Coronary artery myocardial bridges, a common anatomic variant, have an autopsy detection rate of 15% to 65%.In 1960, physicians discovered 1 patient with this condition while performing coronary angiography on a patient, and the concept of myocardial bridges was introduced for the first time. For a long time, mural coronary arteries and myocardial bridges have always been considered benign lesions. With the development of medical research, it has been recognized that myocardial bridges can have an impact on the morphology and hemodynamics of the mural coronary arteries and cause a variety of clinical symptoms. The 16-year-old middle school student Xiao Liu, but from a young age, there is a little activity on the chest tightness, chest pain, shortness of breath, and even fainted in severe cases of strange problems. Xiao Liu and his parents are distressed, went to many hospitals, did an ECG and X-ray examination, visited the doctor countless times, but found nothing wrong. Xiao Liu can not play with children of the same age, sensitive, he thought he had a difficult to identify the “strange disease”, and gradually silent, lonely and autistic, Xiao Liu’s mother to see in the eyes of the anxious heart. She wanted to know how their children in the end, I heard that the Fifth Affiliated Hospital of Zhengzhou University, 256-slice spiral CT coronary artery imaging examination is currently the province’s most advanced non-invasive cardiac imaging equipment, with a try to give the child a coronary artery imaging examination of the heart. After the examination, it was found that Xiao Liu’s heart is indeed abnormal, this abnormality is not the usual meaning of heart disease, but congenital vascular variation, medically known as “wall coronary artery” and “myocardial bridge”. Advanced medical science and technology, finally solved the mystery of Liu’s “strange disease”. 44-year-old private enterprise boss Mr. Qin, usually fast heartbeat, encountered a little busy at work, socializing a little more, feel panic, chest tightness, and even sometimes have an indescribable sense of suffocation, he suspected that he had “coronary heart disease”, his family accompanied to the hospital to do a number of such as electrocardiograms and other routine checks, and coronary arteriography, the results of which are No obvious problems were found. The doctor suggested that he do a 64-row spiral CT cardiac examination, but in a number of provincial hospitals for 64-row spiral CT cardiac examination due to nervousness and their own heart rate is too fast, can not be examined. The doctor told him to take medication to lower his heart rate, but he thought that he could not take the medication without identifying the cause. Being in his middle age, he was worried all day long and his mental state was very poor because he couldn’t figure out what kind of disease he had. Later, he heard that 256-slice spiral CT can be used for heart examination without controlling the heart rate, so he came back to try again accompanied by his family. During the examination, also because of nervousness, the cardiac monitor showed that his heart rate had reached 130 beats per minute, but the doctor still finished the examination for him smoothly and diagnosed a walled coronary artery with a thickness of 0.2cm in the middle of the anterior descending branch of the left coronary artery and accurately measured his myocardial function through four-dimensional reconstruction of cardiac cycle, and then measured his myocardium. He was able to accurately measure the degree of compression of his myocardial bridge on the coronary vessels, and the questions in his own mind were finally answered. Mr. Xu Hongwei, Director of the Radiology and Imaging Department of the Fifth Affiliated Hospital of Zhengzhou University, explained the causes of the disease to us in detail. General people’s coronary arteries walking in the heart under the epicardium of the fat tissue, and Liu’s part of the coronary arteries into the heart muscle, walking in the myocardium for a distance and then floated out to the surface of the myocardium, this blood vessel is called the wall of the coronary arteries, the myocardial fibers covering the surface of the outer shape of the bridge is known as the myocardial bridge. Because myocardial fibers cover part of the coronary vessels, when the heart contracts, it will squeeze the blood vessels, resulting in relative narrowing of the coronary lumen, affecting the local blood supply to the myocardium, thus triggering palpitations, angina pectoris, arrhythmia, myocardial infarction and even sudden death. Myocardial bridges mostly occur in the anterior descending branch of the left coronary artery. In recent years, reports of myocardial bridges leading to arrhythmias, supraventricular tachycardia, atrioventricular block, myocardial ischemia, acute coronary syndromes, and sudden death after cardiac transplantation have begun to gradually increase. At present, conventional coronary angiography is still the gold standard for clinical diagnosis of myocardial bridges, but for various reasons, the clinical detection rate is less than 2%, and most of the patients are underdiagnosed by the clinic. The cases of Mr. Liu and Mr. Qin mentioned in this article were undiagnosed for many years because most of the doctors did not recognize this disease and the lack of specificity of routine physical examination. The different clinical manifestations of myocardial bridges are related to their thickness, the length of the walled coronary arteries, and the degree of vascular compression. Patients like Xiao Liu should try to avoid emotional excitement or minimize heavy physical work in their daily lives. Treatment can be given beta-blockers, calcium antagonists and other drugs to relieve symptoms. Director Xu Hongwei said, to their department for coronary CT examination of more than 2,000 cases of suspected coronary heart disease patients, nearly 60% of the patients were examined with myocardial bridges, due to the 256-layer CT in the cardiac examination of the ordinary 64-row spiral CT machine in the scanning speed has made a qualitative leap, the patient does not need to take medication during the examination of the heart rate will be controlled at the rate of less than 70 times a minute, and at the same time a higher resolution to make the cardiac images show a clearer, by simulating the cycle of the heart. More clear, through the simulation of the cardiac cycle of four-dimensional reconstruction technology, so that clinicians have a clear picture of the patient’s real cardiac dynamic movement status and coronary blood supply, so that the detection rate of patients with myocardial bridge and diagnostic accuracy have reached 100%, but also for the cardiologist’s diagnosis and treatment to provide a reliable basis for the 256-slice CT machine in the whole-body vascular examination of the many advantages with the increasing number of patients and continue to come to the forefront. The advantages of 256-slice spiral CT in whole-body vascular examination are being emphasized with the increasing number of patients.