Related tests
1.Laboratory tests
Routine blood tests: normal or reduced total white blood cell count and reduced lymphocyte count in early stages.
liver and kidney function: elevated liver enzymes and muscle enzymes in some patients.
elevated serum C-reactive protein and sedimentation, normal calcitoninogen.
Coagulation function: D-dimer may be elevated in severe cases.
2.Imaging examination
CT examination early manifests as multiple small patchy shadow and interstitial changes, the outer lung band is obvious, progressing to multiple ground glass shadow and infiltrative shadow in both lungs, etc. In severe cases, there may be lung parenchymal changes, even “white lung”, pleural effusion is rare.
3.Detection of pathogens
Collect specimens from the upper and lower respiratory tract of suspected cases, such as bronchial or alveolar lavage fluid, deep cough sputum, as well as serum from the early onset and 14 days after onset, and perform real-time fluorescence RT-PCR to detect positive 2019-nCoV nucleic acid (i.e. new coronavirus nucleic acid detection kit).
Diagnostic criteria
Suspected cases: 2 of the following were met
1. epidemiological history: history of travel or residence in Wuhan within two weeks prior to the onset of illness; previous contact with patients with fever with respiratory symptoms from Wuhan within 14 days prior to the onset of illness; or aggregated illness.
2. Clinical manifestations: fever; imaging features of viral pneumonia; normal or reduced total white blood cell count or reduced lymphocyte count early in the onset of the disease.
Confirmed cases: on the basis of suspected cases, meeting 1 of the following
1, pathogenic testing: collection of pharyngeal swabs, sputum or specimens of lower respiratory secretions for positive nucleic acid testing of novel coronaviruses.
2. Viral gene sequencing: highly homologous to known novel coronaviruses.
References
[1] Hubei Technical Publishing House, “Handbook for the prevention of novel coronavirus pneumonia
[2] Life Times, “Epidemic Q&A