Usually, alcohol consumption is not recommended within 1 week of a patient taking cephalosporins. Most cephalosporins have methiotetrazole side chains, such as cefoperazone, ceftriaxone, cefaclor, cefadroxil, cefadroxil, etc. When alcohol is consumed after taking such drugs, the activity of acetaldehyde dehydrogenase in the patient’s liver is inhibited, which affects the metabolism of alcohol in the liver and causes acetaldehyde to accumulate in the body, causing headache, chest tightness, cyanosis of the lips, dyspnea, excessive sweating, fatigue, flushing, nausea, vomiting, hallucinations, and Symptoms such as decreased blood pressure and even anaphylactic shock can occur. It takes about 5 days for the activity of acetaldehyde dehydrogenase to be fully revived, so it is not recommended to drink alcohol within 1 week after taking cephalosporins. In addition, disulfiram, metronidazole, furazolidone, toluenesulfonylurea, chlorosulfopropuron and other drugs can cause disulfiram reactions, so patients should not drink alcohol within 1 week after taking the drugs.