Hand fungal infection is mainly ringworm, which can be completely eradicated by topical medication or oral medication. 1. Topical medication: when the fungal infection of the hand appears red spots, itching and other symptoms, patients can use topical miconazole cream, amorphophallus cream, etc., which can effectively inhibit and kill the fungus and alleviate the symptoms of fungal infection. When the fungal infection caused by hand skin keratinization thickening, can be used externally salicylic acid ointment, benzoic acid ointment and other drugs to soften the keratin, to help antifungal drugs work better. 2. Oral medication: When the effect of external medication is not satisfactory, patients can take oral itraconazole capsules, terbinafine hydrochloride tablets and other antifungal medications as prescribed by the doctor to achieve the therapeutic purpose. Patients should pay attention to hand hygiene, keep the skin clean and dry, and avoid contacting unclean articles. In addition, the prognostic effect of fungal infection is related to the patient’s immune function condition, the timing of treatment, the severity of the disease and other factors. If the patient’s body immunity is poor, serious condition, etc., there is a possibility of recurrence. All of the above drugs should be used in accordance with medical advice. In order to completely cure the fungal hand infection, patients should go to the hospital for consultation and relevant treatment under the guidance of professional doctors.