High blood uric acid leads to bone and joint pain in the early stage of the disease can be oral non-steroidal anti-inflammatory drugs, colchicine, glucocorticoid treatment, and in severe cases, surgery can be considered. 1. Early treatment: high blood uric acid leading to bone and joint pain is mainly considered gouty arthritis, early in the disease can be oral non-steroidal anti-inflammatory drugs, such as celecoxib and so on, colchicine and glucocorticosteroids, such as prednisone and other analgesic, anti-inflammatory treatment. The use of drugs need to except contraindications, the use of drugs need to be closely monitored during the adverse drug reactions, need to be taken under the guidance of a doctor. 2. When the symptoms are serious: for long-term high blood uric acid, can be due to uric acid crystals in the joints lead to osteoarthritic cartilage damage, lesions, persistent pain and gradually aggravate the symptoms. At this time, the effect of drug treatment is poor, so we can consider arthroscopic joint cleaning, joint fusion or arthroplasty and other surgical treatment. In addition, high blood uric acid causing bone and joint pain need to pay attention to daily low purine diet, gout symptoms should be as early as possible to the regular hospital rheumatology and immunology, orthopedics and other related departments, follow the doctor’s instructions for diagnosis and treatment, do not self-medication.