When mulberry and American ginseng are used in the treatment of premature ejaculation, the exact dosage is not clearly defined and should be followed by the doctor. In the Pharmacopoeia, the daily dosage for adults is 9-15g of mulberry and 3-6g of American ginseng. Radix Panax Ginseng has the effect of tonifying qi and nourishing yin, clearing heat and generating fluids, while mulberry can nourish yin and replenish blood (nourishing the blood in the body), generating fluids and moisturizing dryness. Used together, the two can treat premature ejaculation caused by deficiency of yin in the liver and kidney (insufficient yin in the liver and kidney), which is mainly manifested as easy lifting of the yang, lumbar and knee soreness and weakness (a feeling of soreness and weakness in the lumbar and knee areas), five heartburns and heat (heat in the hearts of the two hands and two feet, and self-consciousness of being irritated by heat in the heart and chest), hot flushes (a burst of fever), night sweating (abnormal sweating after falling asleep, and stopping of sweating upon waking up) and other disorders. In addition, when mulberry is used, it should be noted that it is not suitable for patients who have diarrhea with cold spleen and stomach. The adverse reactions and contraindications of American ginseng are not clear, but it should not be taken by patients with Yang deficiency, internal cold and cold-dampness. Premature ejaculation patients are advised to go to a regular hospital, under the guidance of a professional physician to identify the evidence of treatment.