Diabetic nephropathy stage four blood sugar and blood pressure control is good, the development of stage five about an average of about five years, but the specific time varies from person to person, can not be generalized. Diabetic nephropathy can be mainly divided into five stages, in which the clinical manifestation of stage four is a large amount of proteinuria, and the patient may have obvious edema, while stage five indicates that the patient’s condition has basically developed into uremia, which is a time when the damage to the kidneys will be very serious. Generally speaking, the time from diabetic nephropathy stage IV to stage V is related to the control of blood sugar and blood pressure. If the patient’s condition is well controlled, it takes about 5 years on average for Diabetic Nephropathy Stage IV to develop into Stage V. However, the exact time varies from person to person and cannot be generalized. If patients take some suitable medications, such as Captopril, Repaglinide, etc., under the guidance of doctors to control the development of blood pressure as well as blood glucose in stage IV, then they can maintain their condition better and slow down the progression of kidney disease. However, if the blood sugar and blood pressure are not controlled in time, it may progress to diabetic nephropathy stage V more quickly. Patients with diabetic nephropathy are advised to visit regular hospitals in time and standardize the treatment under the guidance of doctors.