Screening for neonatal eye disease is divided into primary and repeat screening, with primary screening 2-7 days after birth and repeat screening, at 42 days after birth as well as at 3 and 6 months of age. A complete operational approach is taken, with pre-screening education to parents to make them aware of the incidence of eye disease in newborns and the adverse effects it can have on their children, and that early detection, early diagnosis, and early intervention are necessary to minimize these adverse effects. The newborn eye disease re-screening and re-screening notification forms are distributed, and the disease is well explained. The ease of understanding and detailing of the screening process has a direct impact on the screening rate. For high-risk infants, especially those with retinopathy of prematurity weighing less than 1500g and less than 32 weeks of gestation, a registration and follow-up system should be established, and those who are not re-screened on time should be notified by phone in time to avoid missing the best time and causing lifelong disabilities.