In patients with acute pancreatitis, the indications for surgery include the following: 1. acute abdomen caused by other factors that cannot be excluded, such as complications of acute obstructive purulent cholangitis; 2. necrosis or infection of the peripancreatic tissue, which is ineffective after conservative treatment; 3. continued deterioration after conservative treatment; 4. fulminant pancreatitis, which continues to deteriorate after 24 hours of rescue treatment and develops multi-organ insufficiency; 5. complications, such as intestinal fistula, pseudocysts of the pancreas, hemorrhage, etc.