Causes of overeating: The pancreas is an important organ that secretes digestive enzymes, and the pancreatic juice it secretes contains a variety of enzymes that can digest proteins, fats and carbohydrates. Under normal circumstances, these enzymes exist in the form of inactive “zymogen” in the pancreas, which is the predecessor of enzymes and does not digest its own tissues, but when people overeat, it will stimulate the secretion of large amounts of pancreatic juice, causing a sudden increase in the pressure in the pancreatic duct, resulting in the rupture of the pancreatic vesicles and the entry of these “zymogen” into the pancreas and its surrounding tissues. When these “enzymes” enter the pancreas and its surrounding tissues, they are activated and turn into digestive enzymes that can digest their own tissues and produce different degrees of pancreatic damage and inflammatory reactions. Heavy alcohol consumption: Alcohol can cause papilledema and affect the drainage of bile and pancreatic juice. Alcohol can also lead to pancreatic hypersecretion, which can also trigger acute pancreatitis. It has been clinically found that if you suffer from gallstone disease, biliary ascariasis, cholecystitis and other diseases that can cause poor bile excretion, then it is more likely to trigger pancreatitis after overeating. Biliary tract disorders: Inflammation in the gallbladder or biliary tract can cause the papillary opening to become congested and edematous; small gallstones can also block the papillary opening; roundworms in the intestines like to drill the papillary opening, and the dirt on the worms can cause the papillary opening to become inflamed; roundworms can also bring duodenal fluid into the pancreatic duct. Hyperlipidemia: Excessive triglycerides will accumulate in the blood vessels, liver and other tissues, causing atherosclerosis, coronary heart disease, fatty liver and other diseases. If triglycerides accumulate in the pancreas, the activated pancreatic enzymes will break down the triglycerides into large amounts of free fatty acids, and the remaining free fatty acids that are not bound to albumin are highly toxic, which can easily damage the pancreas and cause acute pancreatic inflammation. Clinical manifestations The onset of the disease is often l to 2 hours after a full meal or alcohol consumption. Typical pancreatitis starts very suddenly, mostly after a full meal or alcohol abuse, common signs and symptoms: ① abdominal pain: upper abdominal pain is the most common symptom of acute pancreatitis, most patients feel severe and continuous pain in the abdomen, upper abdominal pain is mostly aggravated after meals, eating greasy food will also aggravate abdominal pain. ②Vomiting: About 2/3 of patients with acute pancreatitis have vomiting, and the number of vomiting varies. ③Fever: The presence or absence of fever or the level of fever is related to the severity of pancreatitis, and a high fever indicates a serious condition. Physical examination: Once epigastric pain occurs, the patient or family members can press the abdomen with their hands, and the patient feels the pain increase (mainly in the upper middle abdomen and left upper abdomen), and when the hand is suddenly lifted, the patient feels the abdominal pain even more (this phenomenon is called “rebound pain” in medicine). ⑤ Laboratory and other tests: increased white blood cells (l-20,000/mm3); increased blood and urine amylase measurements; enlarged pancreas visible on ultrasound; CT examination is sometimes helpful in the diagnosis of pancreatitis. If the patient has consumed alcohol, especially strong alcohol, or binge drinking a few hours before the onset of the disease, and has suffered from biliary tract disorders or is suffering from biliary tract disorders, pancreatic duct obstructive disease, recent vomiting or stool roundworms sudden onset of severe abdominal pain, more should be considered an attack of pancreatitis.