1.High pillow position at night, limit salt, give diuretics. 2, 1% methylcellulose or 0.5% hydrocortisone eye drops, use antibiotic eye ointment during sleep, and cover the eyes to prevent corneal damage. 3.Immunosuppressant: Prednisone 60~100mg/d, divided into 3 times orally, for 2~4 weeks, and then gradually reduce the amount in the following 4-12 weeks. In severe cases, methylprednisolone 0.5~1.0g can be added to saline drip, every other day, 2~3 times in a row and then changed to oral prednisone. Other immunosuppressants such as cyclophosphamide can also be tried. 4, severe protruding eyes, exposure keratitis or compressive optic neuropathy, feasible orbital decompression surgery or retrobulbar radiation therapy to reduce orbital and retrobulbar infiltration. When the effect of prednisone is not good, it can be changed to retrobulbar radiation therapy, usually given a dose of 20Gy, divided into 10 times in two weeks. 5, ATD treatment is preferred for controlling hyperthyroidism, as surgery and 131I treatment may aggravate infiltrative proptosis. 6, L-T450~100mg/d can be combined to prevent hypothyroidism from aggravating proptosis.