Pulmonary blisters are air-containing cavities formed when alveoli expand and rupture due to increased internal pressure, and are benign respiratory diseases that are usually not serious, but if symptoms develop, they indicate a more serious condition. A single pulmonary blister can be cured by aggressive surgical treatment, but in the case of a diffuse pulmonary blister, it cannot be completely removed by surgery, i.e., it cannot be cured completely. When a pulmonary blister is detected on examination, it can be left untreated if it is asymptomatic and observed regularly. If the patient develops dyspnea, hemoptysis, chest pain, etc., or if the patient develops spontaneous pneumothorax or secondary infection, this is a more serious condition and should be treated immediately by a doctor. In the case of solitary pulmonary blister, most patients can be restored to health through surgical or endoscopic treatment. In the case of diffuse pulmonary blisters, surgery is often not a complete cure, but most of them are related to chronic obstructive pulmonary disease and can be treated with bronchodilators to improve symptoms. Patients need to adjust their psychological state after the appearance of pulmonary blister, treat the disease correctly and avoid excessive worry. And pay attention to quit smoking and alcohol, as well as avoid breath-holding, violent coughing, heavy lifting, etc., to avoid the rupture of pneumothorax, hemopneumothorax or secondary infection.