Azoospermia is one of the male sperm semen abnormalities that have a great impact on men’s health and fertility and therefore cause concern for men of all ages, and it is crucial to have a detailed examination. Sperm and eggs are the basic elements to maintain fertility and one cannot be missing. If there is no sperm present in the ejaculated semen, then the rate of fertilization and egg union is zero. This affects the integrity and happiness of the family. For fertility, which is an important matter for every family and traditionally considered to be a female matter, men suffering from azoospermia are also not fertile and patients are reminded to pay attention to azoospermia treatment to make their families complete as soon as possible. The treatment of azoospermia requires a good all-round examination to understand the type and cause of the disease before the treatment plan can be implemented. What tests should be done for azoospermia? The first thing is to have a detailed understanding of the basic common reasons why men have no sperm and to do a comprehensive physical examination with the help of advanced instruments, especially the examination of the reproductive system. Examination 2: Semen analysis and examination of sperm count, morphology and vitality should be done. Examination 3: Genetic examination to identify whether male azoospermia is congenital or acquired. Examination 4: Testicular biopsy for research laboratory analysis and examination to understand whether the testes have no sperm production ability or have sperm but cannot be exported out of the body. Examination 5: The human endocrine system is closely related to human health. Laboratory examinations on endocrine aspects mainly include the determination of endocrine functions of the thalamus, pituitary gland, adrenal gland and gonads. Doctors point out that increased work pressure, serious environmental pollution and poor living habits are likely to affect sperm quality. Azoospermia can be induced by picky and partial eating, smoking and alcohol abuse, unclean sexual intercourse, prolonged sitting, high temperature radiation, etc. We hope that men will pay more attention in their lives and reverse bad lifestyle and habits to maintain sperm health and fertility.