Waking up from sleep with numbness in the right hand may be caused by nerve pressure, and can also occur if there is cerebrovascular disease, such as cerebral infarction. The disease is an acute ischemic cerebrovascular disease that occurs mostly in middle-aged and elderly people. Most patients have the disease in a quiet state or during sleep, and can present with a variety of different signs and symptoms, including limb sensory impairment, motor impairment, and also speech dysfunction. If the infarct focus is in the basal ganglia area, hemiparesis and hemianopia can occur, and if the focus is in the thalamus, the main manifestation is sensory impairment. If necessary, cranial CT should be examined to clarify the diagnosis, and hospitalization should be promptly after the onset.