Non-uniform fatty liver can be treated by controlling diet, strengthening exercise, and giving drugs to protect liver and reduce fat if necessary. 1. Diet control: patients with mild cases may not have any manifestations, it is recommended to control diet, eat more fresh fruits and vegetables, avoid tobacco, alcohol, high-fat food intake, and review liver ultrasound and liver function regularly. 2. Strengthening exercise: through strengthening exercise, it is conducive to improving physical fitness, reducing weight and avoiding further aggravation of fatty liver. 3. Medication: If combined with liver injury, suitable medication can be given under doctor’s guidance, such as polyene phosphatidylcholine and other drugs, which can alleviate liver cell injury; lipid-lowering drugs, such as atorvastatin, can reduce lipid content, avoid fat accumulation in the liver, and also alleviate the condition of patients. Patients with non-uniform fatty liver should combine with doctor’s advice for early treatment to avoid further aggravation.