Compound lidocaine cream has various clinical uses, and its specific use time is closely related to the purpose and intention of use, so it cannot be generalized. Compound lidocaine cream can block the nerve transmission on the skin surface, so it has local anesthetic effect, and its main pharmacological components are lidocaine and proparacaine. It is mostly used clinically for surgical anesthesia on the skin surface, medical aesthetics, laser treatment, debridement and drainage, lumbar puncture, abdominal puncture and thoracic puncture. It is applied to the skin surface about 20 minutes before surgery and can produce local anesthetic effect after about 20 minutes to facilitate surgical operation. In addition, patients can also apply compound lidocaine cream to the glans of the penis about 10 minutes in advance, which can reduce the sensitivity of the penis and thus prolong sexual life. In addition, the use of compound lidocaine cream should be started in small doses, and the exact amount will vary from person to person.