Whether you can exercise after one month of anticoagulation for popliteal vein thrombosis should be determined by the condition of the thrombus. Usually, popliteal vein thrombosis after one month of treatment belongs to the chronic phase, the condition is relatively stable, and appropriate exercise can be carried out. However, it cannot be ruled out that the thrombus is still large and exercise is not appropriate, and this should be determined on a case-by-case basis. Popliteal vein belongs to deep vein, and the staging of DVT is as follows: acute stage: within 7 days after the onset of the disease; subacute stage refers to the 8th to 30th day after the onset of the disease (one month); chronic stage refers to the 30th day after the onset of the disease. Therefore, popliteal vein is already in the chronic phase after one month of thrombotic anticoagulation, when exercise is less likely to trigger pulmonary embolism. However, before exercise, the popliteal vein should be examined ultrasonographically for thrombus. However, patients should pay attention to not do strenuous exercise, can be a small amount, many times walking, at the same time, it is best to wear compression stockings during exercise, to promote the venous return of the lower limbs, to reduce the swelling and pain of the lower limbs. In conclusion, after one month of anticoagulation for popliteal vein thrombosis, patients should follow the doctor’s instructions for appropriate exercise.