Meige syndrome is typically characterized by eyelid spasms and involuntary movements of the oral and lower collar muscles, and is often misdiagnosed clinically as facial muscle spasms, neurosis, and myasthenia gravis. Meige syndrome caused by cervical spondylosis is less common clinically. One case of Meige syndrome from cervical spondylosis arch I was admitted in November 2005 and is reported as follows. 1. Case report Patient, female, 48 years old. Half a month ago, both eyes were dangerously drooping, involuntarily closed and difficult to open, recently aggravated, but can be opened in the morning, accompanied by shyness and dry eyes, accompanied by paroxysmal spasm of the mouth and lips, emotional fluctuations, exertion and neck discomfort and other triggers to aggravate the symptoms. On examination: both eye fissures were small, efforts were made to open the eyes, the size of the eye fissures was normal, transients were frequent, and the muscles of the mouth and lips contracted symmetrically. The symptoms did not improve after 1 week of treatment with subflubercidinol and carbamazepine. The patient presented with neck discomfort with dizziness. On examination: cervical flexion, restricted movement, left deviation of C4 spinous process, pressure pain (+), radicular sign (-), pathological reflex (-). MRI showed: osteophytes, mild protrusion of C4 and 5 intervertebral discs, no spinal cord compression, no intramedullary abnormalities; color Doppler ultrasonography of cervical vessels showed: insufficient blood supply to the vertebrobasilar artery; the diagnosis of vertebral artery cervical spondylosis was confirmed. l weeks later, the patient was given hot compresses on the neck and the spinal (fixed-point) rotational repositioning method to correct the C4 spinous process. The patient’s symptoms disappeared after one week of treatment, and the cervical spine sequence and activities were normal. 2, Discussion Meige syndrome, also known as idiopathic blepharospasm oro-anterior mandibular dystonia syndrome, is mostly seen in middle-aged and elderly people. There are three clinical types: blepharospasm, blepharospasm combined with oromandibular dystonia, and oromandibular dystonia. The patient with Meige’s syndrome is a complete case of blepharospasm combined with orofacial and mandibular dystonia, which should be differentiated from facial spasm, myasthenia gravis, and delayed-onset dyskinesia. The etiology and pathological mechanism of Meige syndrome are not yet completely clear, most scholars believe that it may be related to dopamine receptor hypersensitivity, enhanced cholinergic neurological effects and reduced function of γ-aminobutyric acid neurons, so the clinical use of anti-dopamine drugs (haloperidol), blocking dopamine receptor drugs (inosine), can produce a certain effect. Several domestic units have used local injection of botulinum toxin type A to treat Meige syndrome and obtained certain efficacy, but complete consolidation has not been achieved regardless of which drug is used. The author, through the treatment of cervical spondylosis, made the patient’s symptoms disappear, and considered that the occurrence of the disease is related to cervical spondylosis, and the mechanism may be therapeutic by improving the function of sympathetic nerves, but similar reports have not been seen in China, and the specific mechanism needs to be further studied and explored.