The treatment of chronic obstructive pulmonary disease (COPD) caused by compensated emphysema after left upper lobectomy is mainly focused on stabilizing the condition and preventing acute exacerbation, and different treatment strategies need to be adopted according to the condition. The treatment of COPD patients in the stabilization period mainly includes education or persuasion to quit smoking, staying away from dust and pollution, moderate exercise and physical fitness enhancement. At the same time, bronchodilators such as tiotropium bromide and aminophylline can be given to relieve symptoms of shortness of breath, and expectorants such as aminobromine hydrochloride and N-acetylcysteine can also be taken orally to improve symptoms of coughing and sputum. Acute exacerbations in COPD patients are mainly caused by bacterial or viral infections. If bacterial infection, according to the severity of the infection, cefixime, levofloxacin and other antibiotics can be selected anti-infective treatment, and at the same time give bronchodilators such as salbutamol, expectorants such as acetylcysteine and other symptomatic treatment. If necessary, glucocorticoids such as methylprednisolone can be given intravenously. If diagnosed with COPD, it is recommended to consult a doctor in time and standardize the treatment under the doctor’s guidance to avoid delaying the condition.