Hepatic encephalopathy, also known as hepatic coma, is a complication of the liver and a more serious and high mortality liver disease. There are many causes of hepatic encephalopathy, such as severe viral hepatitis, severe toxic hepatitis, or chronic liver cirrhosis. And hepatic encephalopathy occurs most frequently in patients with cirrhosis. There are many factors that trigger hepatic encephalopathy, the more common ones are upper gastrointestinal bleeding, high protein diet, massive potassium discharge diuresis, ascites discharge, uremia, infection or surgical trauma. Therefore it is important to prevent the occurrence of hepatic encephalopathy from these causative factors, and must control the primary disease. If you have hepatitis B, you can first use antiviral drugs for treatment to try to avoid cirrhosis of the liver. Usually, we must have a low salt and low fat diet, reduce the intake of toxic substances (such as long-term intake of large amounts of alcohol), pay attention to reducing the dosage when taking drugs that are more damaging to the liver, and also go to the hospital regularly for relevant laboratory tests to avoid the emergence of toxic liver disease. In conclusion, hepatic encephalopathy is a central nervous system disease caused by severe metabolic insufficiency of the liver and based on metabolic disorders, which must be treated actively.