Can all lymphomas be staged? The staging of lymphoma is mainly used for Hodgkin’s lymphoma, which is divided into 4 stages. Non-Hodgkin’s lymphoma can be staged with reference to it, but since non-Hodgkin’s lymphoma does not metastasize sequentially along the lymph node area, but spreads in a jumpy manner with more extra-nodal invasion, the clinical value of staging is less than that of Hodgkin’s lymphoma, and the tendency of non-Hodgkin’s lymphoma to occur in multiple centers determines that its treatment strategy should be mainly chemotherapy. What is the staging of Hodgkin’s lymphoma? The current medical community usually classifies lymphoma into stages I-IV according to the clinical staging scheme proposed by Ann Arbor in 1966: Stage I – lesion limited to one lymph node area (I) or one organ outside the lymph node receives localized involvement of the lesion (IE). Stage II – The lesion involves 2 or more lymph node areas ipsilateral to the diaphragm (superior or inferior) (II), or the lesion is limited to organs other than lymph nodes and more than 1 lymph node area ipsilateral to the diaphragm (IIE). Stage III – Lymph node lesions appear both above and below the diaphragm (III). It may be accompanied by splenic involvement (IIIS), limited involvement of organs other than lymph nodes (IIIE), or limited involvement of organs other than the spleen and lymph nodes (IIISE). Stage IV – Extensive or disseminated invasion of one or more organs other than lymph nodes, with or without lymph node enlargement. Any involvement of the liver or bone marrow by the lesion is considered stage IV. Each stage is subdivided into A and B. A: no systemic symptoms; B: one of the following systemic symptoms: unexplained fever above 38°C, night sweats, and unexplained weight loss of 10% within 6 months. The accurate staging of lymphoma is closely related to both the formulation of the treatment plan and the prognosis. Your doctor will consult with you and your family, follow the procedure in a planned manner, and take the necessary selective diagnostic steps and ancillary measures.