For seafood allergy with itchy skin, first of all, we need to stop eating seafood products, then consider quick itch relief, and desensitization and other related treatments should be given when the problem is serious, and the following operations can be carried out after judging the severity of skin lesions: 1. If the area of skin lesions is small and the number is small, you can directly apply topical glyburide lotion or hormonal creams, such as dextran cream, mometasone furoate cream, etc.; 2. If the lesions are large and numerous, but the allergic person does not have systemic symptoms such as dizziness, nausea, chest tightness, dyspnea, abdominal pain and diarrhea, he can take second-generation antihistamines such as loratadine and cetirizine orally. When there are no contraindications to hormone use in allergic patients, oral prednisone tablets can also be taken at the same time. In addition to itchy skin, seafood allergy can also lead to respiratory distress, edema, and even shock, and other more serious conditions, which require immediate treatment by a doctor. In general, allergy sufferers should avoid eating seafood or even other foods that are commonly allergenic, such as kiwi, mango, durian, etc., after recovering from the disease, so as to prevent the re-emergence of allergy. Daily diet should be light, eat easily digestible food, avoid greasy, spicy and stimulating food to increase the burden on the digestive tract.