A stomachache without food is usually divided into two cases. One case is a physiological factor, such as stomach acid irritating the stomach lining after the stomach empties, causing a stomachache. The other is a pathological factor, such as due to duodenal ulcer. Patients need to go to the hospital in time to improve the relevant examination and clear the cause for treatment. Common causes and treatments 1. Normal condition: In the state of gastric emptying, stomach acid in the stomach will stimulate the stomach wall, and patients will feel pain. In addition, the absence of food in the stomach and intestines and the acceleration of gastrointestinal peristalsis will cause gastrointestinal spasm, which can also lead to stomach pain, which is a normal condition. Patients eat on time in daily life and consume more soft, easily digestible and light food; 2. Disease factors: This hunger pain is a typical symptom of duodenal ulcer, specifically chronic, rhythmic, periodic burning or dull pain in the upper abdomen, which can be relieved after eating. Patients need to go to the hospital, clear diagnosis after the application of medication as prescribed by the doctor, the application of anti-acid secretion drugs, such as omeprazole, cimetidine, etc., the application of gastric mucosal protective agents, such as bismuth potassium citrate, if there is H. pylori infection, but also the need for quadruple drug eradication treatment. Patients should avoid irregular diet, try to eat regularly and quantitatively, and avoid overeating or eating too much greasy, cold, indigestible, spicy and stimulating food, and eat more fresh vegetables and fruits to avoid further aggravation of gastrointestinal discomfort.