1. What are the triggering factors of neurodermatitis? Neurodermatitis is unknown, from the concept we can understand, its pathogenesis is mostly believed to be related to neuropsychiatric factors triggered by the dysfunction of excitation and inhibition of the cerebral cortex. Patients with neurological dermatitis often suffer from dizziness, insomnia, irritability, anxiety, and other symptoms of neurological weakness. For example, in some children, neurodermatitis can appear or worsen during the stressful rewriting phase of exams. In addition to the above emotional and mental problems that can trigger the onset of neurodermatitis, endocrine disorders, gastrointestinal dysfunction, stimulation of infected lesions, overexertion, as well as scratching, sun exposure, alcohol consumption, and mechanical and physical stimulation can trigger or aggravate neurodermatitis. The incidence of neurodermatitis is greatly increased in some perimenopausal menopausal women, also, after giving endocrine conditioning, the neurodermatitis of these patients will improve accordingly. What is the main danger of neurodermatitis? The main symptom of neurodermatitis is “itching”. The main feature of this itchy discomfort should be described professionally as “paroxysmal intense itching”, and some patients can even itch to the point of “pain”. The itching is most pronounced at night, so most patients suffer from sleep disruption and even insomnia. This itching causes a decrease in sleep quality, which inevitably affects normal work and study the next day. On a daily basis, patients may also develop neurological weakness such as irritability, anxiety and fatigue, which in turn further aggravate the progress of neurodermatitis. In addition, because of the intense itching, many patients scratching serious, can lead to epidermal peeling, and can even cause skin infection. 3. Can neurodermatitis be contagious? It is clear that neurodermatitis is not contagious. The symptoms and diagnosis of neurodermatitis 1, what is the shape of the papules of neurodermatitis? The majority of the onset of the disease is normal skin, itching or friction and other mechanical stimulation, the local skin quickly appear skin texture deepening, becoming rough, medically known as “skin mossy lesions”. The typical rash appears as a flat papule of normal skin color or light red or dark brown color with a little scaling on top. The papules may join in patches and form coin to palm-sized rashes. Most patients have dry skin, the skin becomes hypertrophic and rough, the upper crestal furrow is obvious, the surface can often be seen scratch marks, blood crust and pigmentation. 2.Where does neurodermatitis occur? Neurodermatitis most often occurs in the neck, lumbosacral region, both elbows and other parts of the body. The back, inner femur, perineum, scrotum and other parts are also common. 3.Why is itchiness more severe at night in neurodermatitis? All pruritic skin diseases, including neurodermatitis, have more pronounced itching at night. Because most patients are in a busy work and study during the day, the itchy discomfort decomposed, the performance will be mild, but at night, the environment is in a quiet state, attention is relatively focused, itchy discomfort is not in mind to be amplified, so feel more serious itching at night. 4.How to distinguish neurodermatitis from eczema, psoriasis, lichen planus, and skin amyloidosis? The main points of differentiation with the following diseases: (1) eczema: Most of them refer to the differentiation of chronic eczema. The disease usually evolves from acute or subacute eczema, without a certain site of predilection, and the course of the disease can be characterized by flowing water and exudation. The key point is that the lesions of eczema have unclear boundaries, whereas neurodermatitis is a moss-like plaque with clear boundaries. (2) Psoriasis: This is medically referred to as psoriasis. Most lesions are more generalized, and in addition to skin damage, other organs are also damaged, such as hair (fascicled hair), nails (thimble-like nails), and tongue (map tongue). Psoriasis lesions have typical features such as flaky or mica-like scales, thin film phenomenon, and punctate bleeding. Some may be combined with joint and other systemic damage. There may be a family history. (3) Lichen planus: mostly purplish red, polygonal flat papules. If the refractive Wechsler’s lines are visible after rubbing with paraffin oil, it can be an important diagnostic basis. (4) Cutaneous amyloidosis: most commonly found on the front side of the calf, the rash is characterized by round papules of the size of rice grains to mung beans, densely packed into patches, but most of them do not fuse with each other, and some of them are arranged in a string of beads. It is worth mentioning that the above-mentioned diseases are sometimes difficult to distinguish from neurodermatitis, and the ultimate golden indicator for identification is skin pathology biopsy. 5.Does neurodermatitis require laboratory tests to confirm the diagnosis? It is not difficult to diagnose neurodermatitis based on the typical mossy skin lesions, the location of the lesions, the paroxysmal itch and other features. Most laboratory tests are not required. However, if it is suspected but the clinical symptoms are not typical, a skin pathology biopsy can be done to clarify.