Neurodermatitis, also known as chronic simple moss, is characterized by mossy skin and intense pruritus. The etiology is unclear, and its causative factors include mental factors, irritating foods, endocrine disorders local irritation, etc. Neurodermatitis is mostly seen in young adults aged 20 to 40 years. The symptoms of the disease start with localized itchiness, and after scratching, pinhead to rice-sized round or polygonal flat papules appear, firm and shiny, and may be accompanied by a small amount of scales. Clinical manifestations can be divided into limited and disseminated according to the extent of involvement: 1. Limited: Mostly seen in young and middle-aged people. The lesions are usually found on the neck, elbows, lumbosacral region, medial femur, female pubic area, scrotum and perianal area, etc., and are mostly confined to one or symmetrically distributed on both sides. The basic lesion is a polygonal flat papule of needle point to rice grain size, light red, light brown or normal skin color, solid and shiny texture, the surface can be covered with a small amount of furfurous scales, the lesion gradually fused and expanded, forming moss-like changes, the edge of the lesion can be seen scattered flat papules, the boundary is clear, can be round, round-like or irregular shape. 2. Disseminated: It occurs in adults and the elderly. The lesions are widely distributed in the eyelids, scalp, trunk, limbs, etc., and are mostly mossy, with scratch marks or blood crusts in and around the lesions. Paroxysmal pruritus is often intensified by local irritation and mental agitation, and is obvious at night. The disease has a chronic course and recurrent episodes that do not heal over the years.