It is a common chronic skin disease characterized by intense itching and mossy skin. The cause of neurodermatitis is not fully understood in modern medicine, but may be due to disorders of cortical inhibition and excitation, mental tension, anxiety, depression, local irritation (such as friction, sun exposure, excessive sweating), as well as indigestion, alcohol consumption and spicy food can trigger or aggravate the disease. The onset of the disease is mainly through three links: itching, scratching, and thick. Because the itch can not resist, scratch, but often the more scratching the more itchy, repeated scratching makes the skin thicken, the result becomes a vicious circle: the more itchy the more scratching, the more scratching the more thick, the more thick the more itchy. The more itching, the more scratching, the thicker, the thicker and the more itchy. The skin becomes a hypertrophic plaque. The selected comprehensive therapy has the advantages of quick itch relief, quick elimination of skin lesions and low recurrence rate. 1.TCM diagnosis and treatment conditioning 2.Fire acupuncture to promote lesion remission 3.Hyperbaric oxygen therapy (hyperbaric oxygen can significantly improve blood oxygen tension, blood oxygen content and oxygen dispersion distance. Improve microcirculation, strengthen aerobic metabolism, make the whole body skin get more oxygen supply. Promote epithelial growth. Accelerate the healing of skin lesions)