The difference between fungal and bacterial infections of the glans is mainly in terms of etiology, clinical symptoms and laboratory tests. 1. Etiology: Fungal infection of glans is usually caused by Candida albicans infection, while bacterial infection of glans is mainly caused by Staphylococcus aureus, Streptococcus and other bacterial infections. 2.Clinical symptoms: (1) Fungal infection of the glans: the patient’s glans and the surface of the coronal groove will have white cheese-like secretion in the form of tofu dregs. And there may be obvious erythema on the surface of the glans, with a smooth surface and clear borders. (2) Bacterial infection of the glans: the patient’s penile skin will be swollen and red, and there is a tingling and burning sensation on the head of the penis. The glans and the inner surface of the foreskin may be congested, vesicles, oozing, and may even bleed. 3. Laboratory examination: the gold standard for distinguishing between fungal and bacterial infections of the glans is to perform smear or bacterial culture of glans secretions to identify the causative bacteria. When patients have glans, they should seek medical treatment in time, and after clarifying the causative bacteria, targeted treatment will be carried out.