The acne here refers to lesions such as pimples and blisters. The soles of the feet long a lot of small pimples very itchy may be related to tinea pedis, eczema, sweat herpes, etc., need to be on the cause of the drug treatment, physical therapy, etc.. 1. For tinea pedis, you can follow the doctor’s instructions to use ketoconazole ointment and other antifungal ointment, oral terbinafine and other antifungal drugs. 2. For eczema, you can follow the doctor’s instructions for the external use of tacrolimus ointment and other drugs, hydrocortisone cream and other glucocorticosteroids, oral cetirizine and other antihistamines, oral or intravenous prednisone and other glucocorticosteroids, and so on; ultraviolet irradiation of the skin lesions will help the recovery of the lesions. 3. for sweat herpes caused by, can follow the doctor’s instructions external tretinoin urea ointment and other glucocorticoids, tacrolimus cream and other immunosuppressants, oral loratadine and other antihistamines; ultraviolet irradiation of the skin lesions can promote the healing of the skin lesions. It is recommended that the people who have a lot of small pox on the soles of their feet and are very itchy go to the hospital in time to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.