There is no clinical term for the 15 signs before death from small cell lung cancer. Before the death of small cell lung cancer patients, i.e. when small cell lung cancer patients reach the terminal stage, they may show signs such as decreased blood pressure, heart rate, blood oxygen, impaired consciousness, and loss of all deep and shallow reflexes. In addition, because small cell lung cancer is a consumptive disease, when cancer cells metastasize to vital organs or compress vital blood vessels, it will lead to multi-organ failure and different signs: 1. Metastasis to the chest: When small cell lung cancer metastasizes to the chest, pain may appear and the pain will be aggravated when the chest is moved. Pleural effusion will also be produced after involving the pleura; 2. Metastasis to the brain: When small cell lung cancer starts to metastasize from the chest, it will easily invade the brain. After brain metastasis, patients will have obvious headache, nausea, vomiting and extreme weakness, which may lead to deep coma or death. Hypoxic encephalopathy caused by the decrease of lung function will also lead to the symptoms of impaired consciousness and coma and lethargy in the end stage of small cell lung cancer patients; 3. Metastasis to the heart: small cell lung cancer metastasis around the heart may invade the pericardium or block the return flow of lymphatic fluid, and when the accumulated fluid reaches a certain amount, it will restrict the pulsation of the heart, which will lead to symptoms such as chest tightness and difficulty in breathing; 4. Compression of superior vena cava: when When the compression of superior vena cava causes obstruction of venous return, patients will experience congestion and edema in the head and neck as well as upper limbs, resulting in superior vena cava obstruction syndrome and endangering patients’ lives; 5.Other: When small cell lung cancer metastasizes to liver, kidney and other parts, patients will experience jaundice, ascites, lower limb edema and so on. In addition, when the tumor compresses the trachea, breathing difficulty and hemoptysis will occur; compression of the recurrent laryngeal nerve will cause hoarseness; compression of the esophagus will cause difficulty in swallowing, and if esophageal fistula is triggered, mediastinal infection may also occur, manifesting as fever and other symptoms. Patients with small cell lung cancer are in pain when they reach the end stage. It is recommended to cooperate with doctors to provide relief treatment and apply morphine to reduce the pain if necessary, and family members should also give extra patience to help patients get through this stage.