The clinical manifestations of pheochromocytoma are mainly related to the excessive secretion of catecholamines, and the clinical performance varies greatly among individuals. The attack is accompanied by intense headache, profuse sweating, palpitations, tachycardia, anxiety, fear, pale skin, nausea, vomiting, abdominal pain, and in severe cases, heart failure and cardiovascular accidents. Individual patients can again develop hypotensive shock, or alternating hypertensive hypotension. There are also arrhythmias, some cases can appear myocardial lesions, such as necrosis, inflammatory changes leading to myocardial function impairment occurs heart failure, and long-term sustained hypertension can lead to left heart hypertrophy, heart enlargement and heart failure; 2, metabolic disorders: high concentrations of adrenal can act on the central nervous system, so that oxygen consumption increases, the basal metabolic rate increases, leading to fever, wasting, accelerated hepatic glycogenolysis, insulin The secretion of insulin is inhibited, resulting in reduced glucose tolerance and increased blood glucose. A small number of patients can develop hypokalemia and hypercalcemia due to tumor secretion of hyperparathyroid hormone; 3. Other aspects: pheochromocytoma can also be a type II multiple endocrine adenoma syndrome, which can be accompanied by medullary thyroid carcinoma, parathyroid adenoma, adrenal adenoma and hyperplasia, and a series of endocrine diseases.