Patients with oral and maxillofacial-head and neck malignancies usually require repair and reconstruction of the tissue defects caused by the surgery while undergoing radical resection of the tumor. When performing the repair and reconstruction, it is important to reconstruct the function and shape of the defect site as well as to reduce the damage to the tissue donor area in terms of function and shape. With the continuous advancement of microsurgical techniques, the application of various vascularized or nonvascularized tissue flaps to repair large maxillofacial soft tissue defects has gained popularity. Commonly used tissue flap repair methods include: adjacent soft tissue flap, forearm flap, pectoralis major muscle flap, latissimus dorsi muscle flap, and rectus abdominis muscle flap. However, these repair methods have a significant impact on the shape and function of the donor area. For example, the forearm flap, which is most widely used in the oral and maxillofacial areas, requires the sacrifice of one major artery in addition to the tissue donor area located in the forearm to cover the wound. Therefore, finding more concealed tissue donor areas and minimizing or avoiding functional impairment and disfigurement of the donor area remains an urgent clinical problem. The advantages of the anterolateral femoral flap are obvious: 1, it is a penetrating flap, without sacrificing the main vessels; the blood supply of the flap mainly comes from the descending or transverse branch of the lateral rotor femoral artery, which does not affect the femoral blood flow after resection; 2, the vascular tip of the flap is longer, 10-14 cm, and the vessel diameter is larger, about 2.11 mm for the artery and 2.13 mm for the vein, which is conducive to vascular anastomosis; 3, the subcutaneous fat below the superficial fascia can be trimmed to make an ultra-thin flap. The subcutaneous fat can be trimmed below the superficial fascia to make an ultra-thin flap for oral repair, which is conducive to the activity of the residual tongue; 4. The donor area is more concealed and can generally be closed directly without the need for another skin graft; 5. It can be performed simultaneously with the head and neck tumor resection surgery without changing the body position. It saves the operation time. The main disadvantages of the anterolateral femoral flap are: 1, the vessel tip diameter is relatively small, the vein is thin, and the technical requirements are high. 2. Anatomic variants of the perforating vessels are common. There are variants of the transverse or medial branch of the lateral femoral artery as the tip, high skin branch blood supply and ischemic type. This increases the difficulty and unpredictability of surgery. 3, The ultrathin flap is more difficult to make, and the general anterolateral femoral flap is thicker and more bulky after folding, which is not suitable for repairing the circumferential hypopharyngeal defect or the cavernous orofacial defect.