Zygomatic macules, also known as acquired nevus of Ota-like macules, also known as zygomatic nevus of brownish-brown color, mainly manifest as symmetrically distributed greenish-brown spots on the cheekbones and nose of young and middle-aged women between 16 and 40 years old, sometimes extending to the temples and forehead. The main feature is the symmetrical distribution of dark gray spots on the cheekbones with a diameter of about 1-5 mm. It is believed that people with cheekbone blemishes have these special melanocytes in their cheekbones since childhood, but they have not yet manifested themselves. As people grow older, these melanocytes become active and produce melanin, which will gradually manifest itself. Q-switched lasers (1064nm, 755nm, 694nm) are very effective in removing these pigments. The interval between each treatment is about 3-6 months. During the treatment process, some patients may have pigmentation, which is manifested as temporary deepening of the laser-treated pigmentation. After the laser treatment, mild skin redness and swelling will appear, which will subside in a day or so, followed by a very thin scab film, which will fall off in about 7-10 days. Usually it will fade down after 3-4 months. The next treatment will be performed after the pigmentation has diminished. Therefore, laser treatment for cheekbone mother spots is a safe and effective treatment.