The definition of remission: complete remission refers to the complete absence of symptoms (normal number of stools and no bloody stools and urgency) accompanied by mucosal healing (normal intestinal mucosa or no active inflammation) on endoscopic review. there is no consensus on the definition of mucosal healing in UC patients. Second, the efficacy assessment: 1, clinical efficacy assessment: applicable to clinical, but because there is no quantitative standards, not suitable for scientific research. ①remission: clinical symptoms disappeared, colonoscopic review of the mucosa is generally normal or no active inflammation. ②Effective: clinical symptoms basically disappeared, and mild inflammation of mucosa was seen on colonoscopy. (3) Not effective: clinical symptoms and colonoscopy did not improve. 2. Modified Mayo score: applicable to scientific research. 3. Definition of relapse: After entering remission naturally or by drug treatment, UC symptoms recur, most commonly blood in stool, diarrhea is also common. It can be confirmed by colonoscopy. Clinical studies are to be selected to define a certain scoring system. 1, the type of recurrence: recurrence can be divided into occasional (≤ 1 time / year), frequent (≥ 2 times / year) and persistent type (UC symptoms continue to be active and can not be remitted). 2.Early relapse: time into remission < 3 months with prior treatment. Fourth, the specific efficacy evaluation related to hormone therapy: 1, hormone ineffective: by the equivalent of prednisone 0, 75mg/kg/d treatment for more than 4 weeks, the disease is still in active phase. 2. Hormone dependence: ① Although the disease can be maintained in remission, prednisone cannot be reduced to 10mg/d after 3 months of hormone therapy; ② Relapse within 3 months of hormone discontinuation.