Why is it important for hyperthyroid patients to be reviewed regularly?

Hyperthyroidism is a common disease. The treatment drugs for hyperthyroidism are relatively simple, and at present the only two commonly used drugs in China are methimazole and propylthiouracil. Because of the high prevalence of the disease, many patients have more or less some understanding of it, of course, there is no lack of wrong understanding. For example, a small portion of “hyperthyroidism” patients for thyroiditis caused by transient hyperthyroidism, no matter with or without medication, the thyroid function will return to normal, so some people will preach that “hyperthyroidism is very good”; Another example is that a small portion of patients with hyperthyroidism is very stubborn, or I did not properly cooperate with the treatment, resulting in repeated discontinuation of medication, and then the treatment will be discontinued. For example, if a small number of patients have stubborn hyperthyroidism, or if they do not cooperate well with the treatment, resulting in relapse after stopping the medication for several times, then some people may claim that “hyperthyroidism treatment can’t get rid of the root”. As a matter of fact, for patients with “hyperthyroidism”, the first thing to do is to exclude the transient hyperthyroidism caused by thyroiditis, and then start the treatment. There are three specific treatment methods: medication, radioactive iodine treatment and surgery. There are advantages and disadvantages to each of the three methods, and drug treatment is the most commonly used treatment in China. Hyperthyroidism is indeed a disease with a high recurrence rate. However, as long as patients adhere to the treatment (low iodine diet, regular use of anti-hyperthyroidism medication, regular checkups), most of the patients can stop taking the medication after one and a half to two years, and the recurrence rate is generally considered to be less than 40% (of course, this statistic is still controversial). Many patients mention why regular reviews are too much of a hassle. The items we review generally include nail function, blood routine, liver function, TRAb antibody and so on. The purpose of reviewing the thyroid function is to adjust the dose of anti-hyperthyroid medication in a timely manner, as reducing the dose too quickly will not cure hyperthyroidism, while on the other hand, failing to reduce the dose in a timely manner may lead to drug-induced hypothyroidism. Although the hypothyroidism caused by oral medication is transient, unlike the lifelong hypothyroidism caused by radioactive iodine, this kind of hypothyroidism can significantly increase the difficulty of subsequent treatment. As an example, I have a patient with hyperthyroidism who had a very high index of hyperthyroidism at the initial onset and was treated in Hong Kong because he worked in Hong Kong. We know that in Hong Kong to see the doctor needs to make an appointment, the procedure is very cumbersome, she followed the initial large dose of methimazole for more than 4 months, the result of the swelling of the whole body, to the hospital for a check, the TSH exceeds the upper limit of the test, suggesting that the serious hypothyroidism, was forced to temporarily stop hyperthyroidism medication, and the addition of eugenol, 3 months later, hyperthyroidism again exacerbated. The blood test and liver function were reviewed to see if there were any adverse reactions to the anti-hyperthyroid drugs. In fact, hyperthyroidism itself may cause low white blood cells and liver function abnormalities, and these adverse effects may also occur with hyperthyroid medications. Most patients are fine after taking the drugs, or only mild abnormalities in the indicators, but a very small number of patients may have serious adverse reactions, the probability is not high, but because the consequences are very serious, so we must pay great attention to this. Regular review is to detect these problems at an early stage. We recommend that blood counts and liver function should be reviewed weekly within the first month of initial treatment.