Some people think that hemorrhoids don’t need to be treated as long as they don’t hurt or bleed, which is not true. If hemorrhoids are left untreated for a long time, they can easily lead to at least four types of harm. 1, anemia: hemorrhoids disease causes the body to lose iron constantly, if long-term blood in the stool, losing a lot of iron, so that the body contains less than normal total iron, can cause iron deficiency anemia. Iron deficiency anemia can be asymptomatic or mild in the early stages, and when the anemia is heavy or progresses faster, there will be pallor, lethargy, loss of appetite, palpitations, increased heart rate and shortness of breath after physical activity, swelling, etc. Some patients can have neurological symptoms such as agitation, excitement, irritability, etc. 2, embedded: another major symptom of hemorrhoids is the prolapse of internal hemorrhoids, prolapsed outside the anus internal hemorrhoids by the clamping of the sphincter muscle, venous reflux is blocked while arterial blood is still constantly input, so that the volume of the hemorrhoid nucleus increases until the arterial blood vessels are pressed closed, thrombus formation appears hemorrhoid nucleus, hardening painful and difficult to send back to the anus. The traditional view is called “strangulated internal hemorrhoids”, but clinically it is more common to see external hemorrhoids with thrombus formation and therefore more painful, when the hemorrhoid nucleus is prolapsed and cannot be returned it is also called “embedded hemorrhoids”, long time embedded hemorrhoid nucleus will also appear lesions. 3, necrosis: hemorrhoid nucleus embedded in the anus, due to a series of pathological changes so that local metabolites accumulate, further aggravating the local edema of the anus, aggravating the embedded hemorrhoid nucleus. This is a vicious circle, so internal hemorrhoids embedded for a long time must appear necrosis, when the necrosis is often limited to the mucous membrane part of the hemorrhoid nucleus, but there are also cases of invasion of other parts of the body. 4.Infection: After the hemorrhoid nucleus is embedded, there are different degrees of infection patients appear urgent, anal swelling and other symptoms, the infection is mostly confined to the anal local, if the strong reset easy to make the infection spread, causing submucosal perianal or sciatic rectal fossa abscess. Fatal portal vein sepsis associated with embedded hemorrhoids has been reported overseas.